Process-scale synthesis of urolithins
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United States of America Patent
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Jul 19, 2016
Grant Date -
Jul 2, 2015
app pub date -
Dec 22, 2014
filing date -
Dec 23, 2013
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Abstract
Disclosed is a method of preparing a urolithin, or an intermediate or analog thereof, having a dibenzo[b,d]pyran-6-one core. The method is especially advantageous for the large-scale preparation of urolithins or intermediates or analogs thereof. The method may optionally include the preparation of a urolithin, or an intermediate or analog thereof, as a pharmaceutically acceptable salt.
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