PKM2 modulators and methods for their use
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United States of America Patent
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Jul 19, 2016
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app pub date -
Oct 16, 2013
filing date -
Oct 16, 2012
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Abstract
Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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