Methods for purifying polysaccharides and pharmaceutical compositions and medical devices containing the same
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United States of America Patent
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Jul 12, 2016
Issued Date -
N/A
app pub date -
Feb 17, 2015
filing date -
Feb 17, 2014
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Methods for removing endotoxin from naturally occurring materials, such as polysaccharides (e.g., agarose and/or carrageenan) are described herein. Polysaccharides that are substantially free of endotoxins and uses thereof are also described. The polysaccharide materials can be isolated from microorganisms, multicellular organisms, such as, algae, plants, seaweed, etc. The method involves the use of acidic and basic solutions to hydrolyze the lipid-polysaccharide bond in endotoxins. Cleaving the fatty acid from the polysaccharide reduces the water-solubility of the fatty acid and enables its removal with an organic solvent such as ethanol. The polysaccharide component can also undergo acidic or basic hydrolysis due to the weak glycosidic bond between the sugar rings.
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International Classification(s)
- 2015 Application Filing Year
- C08J Class
- 2246 Applications Filed
- 1523 Patents Issued To-Date
- 67.81 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- C08J Class
- 0 % this patent is cited more than
- 9 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jan 12, 2028 |
