Ingenol-3-acylates I
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United States of America Patent
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Jul 12, 2016
Grant Date -
Dec 5, 2013
app pub date -
Dec 22, 2011
filing date -
Dec 22, 2010
priority date (Note) -
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Abstract
The invention relates to compounds of general formula (I) wherein R is (C1-C7)alkyl, (C2-C7)alkenyl or (C2-C7)alkynyl; wherein R is substituted with R1; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.
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