Alginate biomaterials for the treatment of hepatic disorders
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United States of America Patent
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Jul 12, 2016
Grant Date -
Sep 30, 2010
app pub date -
Nov 27, 2008
filing date -
Nov 27, 2007
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Abstract
The present invention relates to methods for the treatment of hepatic disorders in a subject in need thereof. More specifically, the methods of the invention are based on the administration, preferably, systemic administration, of a therapeutically effective amount of at least one biocompatible alginate biomaterial, any modification thereof and any combination thereof. The invention further provides methods for sustaining serum albumin levels, and/or reducing serum AST and ALT, in subjects suffering from hepatic disorder. Still further, the invention provides methods for reducing apoptosis and inducing cell proliferation in a damaged liver tissue of a subject suffering of hepatic disorder, using the alginate biomaterial described by the invention.
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