Methods to determine susceptibility to treatment with leukotriene modifiers
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United States of America Patent
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Jul 5, 2016
Grant Date -
Dec 11, 2014
app pub date -
Feb 11, 2014
filing date -
Mar 14, 2008
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Abstract
The present invention provides a method of determining the susceptibility of a subject to treatment with a leukotriene modifier by determining the subject's cysteinyl leukotriene (CysLT) level and the subject's level of eosinophilic airway inflammation and identifying a subject with a high ratio of CysLT levels to eosinophilic airway inflammation as susceptible to treatment with the leukotriene modifier. Also discussed is a method of treatment of subjects who are susceptible to treatment that includes administering a leukotriene modifier to such a subject.
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