Variant activin IIB receptor
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United States of America
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Jul 5, 2016
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app pub date -
Mar 11, 2014
filing date -
Mar 11, 2014
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Abstract
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.
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