Processes for forming amide bonds and compositions related thereto
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United States of America Patent
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Jul 5, 2016
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N/A
app pub date -
Dec 29, 2014
filing date -
Oct 27, 2010
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Abstract
The disclosure relates to methods for producing amide bonds and reagents related thereto. In some embodiments, the disclosure relates to methods of producing an amide comprising mixing an O-silylated thionoester and an amine under conditions such that an amide is formed. In another embodiment, the disclosure relates to mixing a thiolacid, a silylating agent, and an amine under conditions such that an amide is formed.
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