Methods of modifying N-termini of a peptide or protein using transferases
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United States of America Patent
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Jun 28, 2016
Grant Date -
May 21, 2015
app pub date -
Jun 13, 2013
filing date -
Jun 14, 2012
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Abstract
The invention includes a selective method of modifying the N-terminus of a protein using an aminoacyl tRNA transferase. In certain embodiments, the method comprises contacting a solution of the protein or peptide with a transferase and a derivative of a molecule, whereby the N-terminus of the protein or peptide is derivatized with the molecule.
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