Vaccine and therapeutic delivery system

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United States of America Patent

PATENT NO 9376686
SERIAL NO

13624146

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Abstract

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The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed non-pathogenic, commensal bacteria that can express a nucleic acid molecule of a foreign polypeptide, wherein the nucleic acid molecule that encodes the foreign polypeptide is stably integrated into genomic DNA of the bacteria. The foreign polypeptide includes a vaccine antigen that elicits an immunogenic response, an inhibitor of a pathogen, or an immune booster or modulator.

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Patent Owner(s)

Patent OwnerAddress
ADA FORSYTH INSTITUTE INC245 FIRST STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Campos-Neto, Antonio Westborough, US 44 634
Cayabyab, Mark San Jose, US 4 24
Duncan, Margaret Brookline, US 4 23

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