Magnetic resonance imaging contrast agents comprising zinc-containing magnetic metal oxide nanoparticles

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United States of America Patent

PATENT NO 9375495
APP PUB NO 20100143263A1
SERIAL NO

12527482

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Abstract

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The present invention relates to an MRI contrast agent that includes zinc-containing water-soluble metal oxide nanoparticles and has an improved contrast effect. The zinc-containing water-soluble metal oxide nanoparticles are characterized by addition of zinc to a matrix comprising the metal oxide nanoparticles or by substitution of metal in the matrix, resulting in the improved contrast effect of MRI. In addition, the zinc-containing metal oxide nanoparticles of the present invention include the MRI contrast agent t having hybrid structures of “zinc-containing metal oxide nanoparticle—biologically/chemically active material” in which the nanoparticle is conjugated with a bioactive material such as proteins, antibodies, and chemical materials.

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Patent Owner(s)

Patent OwnerAddress
INVENTERA PHARMACEUTICALS INCSEOUL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheon, Jinwoo Seoul, KR 5 24
Jang, Jung-tak Seoul, KR 1 9
Jun, Young-wook Gyeonggi-do, KR 5 26

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