Quinazoline derivative, preparation method therefor, intermediate, composition and application thereof

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United States of America Patent

PATENT NO 9371292
APP PUB NO 20140206687A1
SERIAL NO

14234514

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Abstract

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Disclosed are as represented by Formula (I) a quinazoline derivative and a pharmaceutical acceptable salt thereof, or, an enantiomer, a non-enantiomer, a tautomer, a racemate, a solvate, a metabolic precursor, or a prodrug of both. Also disclosed are a preparation method therefor, an intermediate, a pharmaceutical composition having the quinazoline derivative, and an application thereof. The quinazoline derivative of the present invention is provided with improved anti-tumor activity.

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Patent Owner(s)

Patent OwnerAddress
ZHEJIANG UNIVERSITY866 YUHANGTANG ROAD XIHU DISTRICT HANGZHOU ZHEJIANG 310058
SHANGHAI PHARMACEUTICALS HOLDING CO LTD201203 92 ZHANGJIANG ROAD SHANGHAI PUDONG NEW AREA SHANGHAI CITY SHANGHAI CITY 201203

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Wenteng Hangzhou, CN 3 3
Hao, Yu Shanghai, CN 14 60
Li, Bojun Shanghai, CN 2 3
Liu, Xuejun Shanghai, CN 36 44
Shen, Jingkang Shanghai, CN 22 45
Xia, Guangxin Shanghai, CN 24 45
Yu, Yongping Hangzhou, CN 6 6
Zhang, Chunchun Shanghai, CN 6 42
Zhang, Jing Shanghai, CN 966 8974

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