Cardiomyocyte production
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United States of America Patent
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Jun 14, 2016
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app pub date -
Mar 11, 2013
filing date -
Oct 19, 2009
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Abstract
Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
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