Antibody capable of binding to specific region of periostin, and method of measuring periostin using the same

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United States of America Patent

PATENT NO 9347954
SERIAL NO

14342996

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Abstract

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The present invention provides a method and a reagent for measuring periostin contained in a sample with improved accuracy, a method for improving accuracy in measurement of periostin, and a method of testing for pulmonary fibrosis or interstitial pneumonia with improved accuracy. The antibody of the present invention binds to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin or a cleavage product thereof. The method and the reagent for measuring periostin and the method for improving accuracy in periostin measurement of the present invention is characterized by detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin. The method of testing for pulmonary fibrosis or interstitial pneumonia of the present invention includes the steps of a) measuring the amount or concentration of periostin in a sample derived from a subject, which measuring includes detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin and b) comparing the amount or concentration of the periostin in the sample derived from the subject with an amount or concentration of periostin in a sample derived from a living body not suffering from pulmonary fibrosis and interstitial pneumonia.

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Patent Owner(s)

Patent OwnerAddress
SHINO-TEST CORPORATIONTOKYO 101-8410

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  • 2012 Application Filing Year
  • G01N Class
  • 8064 Applications Filed
  • 6361 Patents Issued To-Date
  • 78.89 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arima, Kazuhiko Saga, JP 4 7
Azuma, Yoshinori Sagamihara, JP 5 30
Hoshino, Tomoaki Kurume, JP 17 22
Izuhara, Kenji Saga, JP 10 81
Ohta, Shoichiro Saga, JP 6 14
Ono, Junya Sagamihara, JP 83 212
Shiraishi, Hiroshi Saga, JP 44 670
Suzuki, Shoichi Saga, JP 628 6863

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  • 3 Citation Count
  • G01N Class
  • 31.44 % this patent is cited more than
  • 9 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges232940745921838355241515882101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500

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