Mass spectrometry systems and methods for analyses on lipid and other ions using a unique workflow
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United States of America Patent
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May 24, 2016
Grant Date -
Dec 3, 2015
app pub date -
Mar 28, 2013
filing date -
Mar 28, 2012
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Abstract
The applicants' teachings provide in some aspects methods and apparatus for mass spectrometric analysis that identify the location of carbon-carbon double bonds, if any, in an analyte by (1) obtaining the m/z ratio of the intact analyte ions, (2) subjecting these ions to collision-induced dissociation and (3) determining relationships between masses and/or mass-to-charge ratios of the intact analyte ions and the fragments produced by such collision-induced dissociation. The methods and apparatus selectively subject analyte ions to ozone-induced dissociation based on those relationships and determine location(s) of carbon-carbon double bonds, if any, from reaction products of ozone-induced dissociation.
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