Method of treating type 1 diabetes with antagonist IL-7 receptor antibodies
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United States of America Patent
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May 24, 2016
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May 22, 2014
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Dec 17, 2013
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Feb 24, 2010
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Abstract
The present invention provides antagonizing antibodies that bind to interleukin-7 receptor (IL-7R). The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acids. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof for the treatment and/or prevention of type 2 diabetes and immunological disorders, including type 1 diabetes, multiple sclerosis, rheumatoid arthritis, graft-versus-host disease, and lupus.
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