Compounds for binding to the platelet specific glycoprotein IIB/IIIA and their use for imaging of thrombi
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United States of America Patent
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May 24, 2016
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Oct 23, 2014
app pub date -
Aug 17, 2012
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Aug 17, 2011
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Abstract
The present invention relates to novel fluorine containing compounds, methods for their preparation, the intermediates of the synthesis, their use as diagnostic agents, especially for imaging of thrombi. The invention relates to positron emission tomography (PET) agents and associated precursor reagents, and methods for producing such radiolaveled agents for imaging of thrombi in a mammalian body. More particularly, the invention relates to small nonpeptide, high-affinity, specific-binding glycoprotein 11b/IIIa antagonists for imaging of thrombi.
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