Isoquinoline, quinoline, and quinazoline derivatives as inhibitors of hedgehog signaling
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United States of America Patent
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May 24, 2016
Grant Date -
Oct 25, 2012
app pub date -
Jun 9, 2010
filing date -
Jun 9, 2009
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Abstract
The invention provides isoquinoline, quinoline, and quinazoline derivatives to treat a variety of disorders, diseases and pathologic conditions, and more specifically to the use of isoquinoline, quinoline, and quinazoline derivatives to inhibit the hedgehog signaling pathway and to the use of those compounds to the treatment of hyperproliferative diseases and pathologic angiogenesis.
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