Multi-transgenic pigs for diabetes treatment
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United States of America Patent
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May 17, 2016
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N/A
app pub date -
Aug 16, 2010
filing date -
Aug 14, 2009
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Abstract
The present invention provides certain animals, and in particular porcine animals, tissue and cells derived from these, which lack any expression of functional alpha 1,3 galactosyltransferase (αGT) and express one or more additional transgenes which make them suitable donors for pancreatic islet xenotransplantation. Methods of treatment and prevention of diabetes using cells derived from such animals are also provided.
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