Computer-assisted karyotyping
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United States of America Patent
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May 10, 2016
Grant Date -
Jan 16, 2014
app pub date -
Jun 19, 2013
filing date -
Jun 19, 2012
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Abstract
A system and method for computer-assisted karyotyping includes a processor which receives a digitized image of metaphase chromosomes for processing in an image processing module and a classifier module. The image processing module may include a segmenting function for extracting individual chromosome images, a bend correcting function for straightening images of chromosomes that are bent or curved and a feature selection function for distinguishing between chromosome bands. The classifier module, which may be one or more trained kernel-based learning machines, receives the processed image and generates a classification of the image as normal or abnormal.
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