Human antibodies that bind human MAdCAM

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9328169
APP PUB NO 20050232917A1
SERIAL NO

11031485

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Abstract

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The present invention relates to antibodies, including human antibodies, and antigen-binding portions thereof that specifically bind to MAdCAM, preferably human MAdCAM, and inhibit MAdCAM. The antibodies comprise the CDRs or variable domains derived from an antibody produced by the hybridoma cell line 7.16.6 (ECACC Accession No. 03090909) or from an antibody comprising the amino acid sequences of SEQ ID NOs.: 34 and 36. The invention also relates to nucleic acid molecules encoding such antibodies and antigen-binding portions thereof, methods of making and using the antibodies and portions, and compositions comprising these antibodies and portions.

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Patent Owner(s)

Patent OwnerAddress
AMGEN FREMONT INC6701 KAISER DRIVE FREMONT CA 94555

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Green, Larry L San Francisco, US 51 1353
Haak-Frendscho, Mary Newark, US 55 742
Kellermann, Sirid-Aimée Menlo Park, US 8 26
Molloy, Elizabeth Sandwich, GB 6 112
Pullen, Nicholas Sandwich, GB 12 137

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