Multimeric IL-15 soluble fusion molecules and methods of using same
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United States of America Patent
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May 3, 2016
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May 15, 2014
app pub date -
Apr 1, 2013
filing date -
Sep 21, 2010
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Abstract
The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).
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