Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same

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United States of America Patent

PATENT NO 9327031
APP PUB NO 20140194520A1
SERIAL NO

14158091

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Abstract

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Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.

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Patent Owner(s)

Patent OwnerAddress
UNITED THERAPEUTICS CORPORATIONSILVER SPRING MD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jeffs, Roger Andrew Chapel Hill, US 7 298
Zaccardelli, David Cary, US 5 85

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