A3 adenosine receptor allosteric modulators

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United States of America Patent

PATENT NO 9326978
APP PUB NO 20130197025A1
SERIAL NO

13800560

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Abstract

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The claimed subject matter relates to allosteric modulation of A3 adenosine receptor (A3AR) and provides for the use of an A3 adenosine receptor modulator (A3RM), for the preparation of pharmaceutical compositions for modulating the A3AR in a subject, as well as pharmaceutical compositions including the same and therapeutic methods including administering to a subject an amount of an A3RM, the amount being effective to modulate A3AR activity. The A3RM according to claimed subject matter are 1H-Imidazo-[4,5-c]quinolin-4-amine derivatives. Also provided are 1H-Imidazo-[4,5-c]quinolin-4-amine derivatives.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICESWASHINGTON DC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brussee, Johannes Rijnsburg, NL 12 53
Göblyös, Anikó Ujszasz, HU 1 0
Gao, Zhan-Guo Rockville, US 2 9
Ijzerman, Adriaan P Haarlem, NL 5 32
Jacobson, Kenneth Silver Spring, US 4 84

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