Genetically modified microorganisms capable of producing beta-glucans and methods for producing beta-glucans

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United States of America Patent

PATENT NO 9322041
APP PUB NO 20140011243A1
SERIAL NO

13935043

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Abstract

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The present invention relates to genetically modified microorganisms capable of producing beta-glucans, characterized in that the genetically modified microorganism overexpresses (i) a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity, and/or (ii) a polypeptide having 1,3-β-D-glucan synthase-activity, compared to a corresponding non-modified control microorganism of the same strain. The present invention also relates to the use of a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity or the use of such a polypeptide for producing β-glucans. Furthermore, the present invention relates to methods for producing β-glucans comprising the introduction of a promoter upstream of a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity thereby increasing the expression of the polynucleotide, or a polynucleotide encoding a polypeptide having 1,3-β-D-glucan synthase-activity into a microorganism being able to synthesize β-glucans.

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Patent Owner(s)

Patent OwnerAddress
BASF SECARL-BOSCH-STRASSE 38 LUDWIGSHAFEN AM RHEIN 67056
WINTERSHALL HOLDING GMBH34119 KASSEL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brockmann, Beata Mannheim, DE 3 1
Fleck, Christian Leimen, DE 13 24
Granström, Mari Mannheim, DE 11 13
Haefner, Stefan Speyer, DE 54 222
Herold, Andrea Weinheim, DE 34 115
Schmidt, Julia Kristiane Heidelberg, DE 7 26
Schröder, Hartwig Nuβloch, DE 49 161
Zelder, Oskar Speyer, DE 141 664

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