RAF kinase modulator compounds and methods of use thereof

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United States of America Patent

PATENT NO 9320739
SERIAL NO

14605834

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Abstract

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Compositions of 1-(3-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-3-(5-(1,1,1, -trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea are provided for modulating the activity of RAF kinases, including BRAF kinase and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder mediated by RAF kinases.

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Patent Owner(s)

Patent OwnerAddress
AMBIT BIOSCIENCES CORP4215 SORRENTO VALLEY BLVD SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abraham, Sunny San Diego, US 35 117
Bhagwat, Shripad S San Diego, US 45 1019
Campbell, Brian T Burlington, US 16 82
Chao, Qi San Diego, US 36 558
Faraoni, Raffaella San Diego, US 6 77
Holladay, Mark W San Diego, US 51 756
Lai, Andiliy G San Diego, US 40 1101
Rowbottom, Martin W San Diego, US 26 119
Setti, Eduardo San Mateo, US 17 111
Sprankle, Kelly G Vista, US 20 371

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