Biosensor for detection of subclinical ketosis

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United States of America Patent

PATENT NO 9316591
SERIAL NO

14617346

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Abstract

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A method of detecting subclinical ketosis in a dairy animal comprises the steps of: obtaining a sample from the dairy animal, the sample containing one of a serum sample or a milk sample; incubating a mixture of the sample and a reactant containing NAD+-functionalized quantum dots to produce an incubated mixture; irradiating the incubated mixture with optical radiation of a first wavelength so as to emit fluorescent radiation of a second wavelength from the incubated mixture; irradiating a photodetector with the fluorescent radiation so as to generate an electrical signal; and performing data acquisition using the photodetector electrical signal to determine a BHBA concentration for the sample.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF GUELPH50 STONE RD E CATALYST CENTRE AXELROD INSTITUTE OF ICHTHYOLOGY (BUILDING 92) GUELPH N1G 2W1

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Longyan Guelph, CA 1 1
Neethirajan, Suresh Guelph, CA 3 10
Weng, Xuan Guelph, CA 2 8

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