Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
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United States of America Patent
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Apr 19, 2016
Grant Date -
Nov 21, 2013
app pub date -
Jan 25, 2012
filing date -
Jan 24, 2011
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Abstract
Described herein are antigen binding proteins that bind to pathogenic mycobacteria-derived Mannose-Capped Lipoarabinomannan (ManLAM) and methods and kits for using and making the antigen binding proteins. Also described herein are antigen binding proteins that bind to the alpha 1-2 linkage mannose caps of ManLAM, antigen binding proteins that bind to a mannose cap with up to three alpha 1-2 linked mannose residues, and antigen binding proteins that bind to LAM with a mannose sugar capping motif.
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