Compositions comprising the NC2 domain of collagen IX and methods of using same
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United States of America Patent
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Apr 19, 2016
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Jun 20, 2013
app pub date -
Nov 23, 2012
filing date -
May 26, 2010
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Abstract
The present invention relates to the newly identified timerization initiating and stagger determining capacity of the NC2 domain of collagen IX. The invention further relates to a hexavalent molecular building block wherein the linkage of additional moieties to the amino and carboxyl terminals of monomers comprising the NC2 domain of collagen IX promotes the directed association of those moieties via the trimerization initiating and stagger determining capacity of the NC2 domain of collagen IX.
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