Antibacterial agents: aryl myxopyronin derivatives
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United States of America Patent
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Apr 19, 2016
Grant Date -
Jul 16, 2015
app pub date -
Jun 19, 2013
filing date -
Jun 19, 2012
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Abstract
The invention provides compounds of formula la, lb and Ic: [Formula Ia, Ib, and Ic] and salts thereof, wherein variables are as described in the specification, as well as compositions comprising a compound of formula Ia-Ic, methods of making such compounds, and methods of using such compounds, e.g., as inhibitors of bacterial RNA polymerase and as antibacterial agents.
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