Preparation enhancements and methods of use for MALDI mass spectrometry
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United States of America Patent
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Apr 5, 2016
Grant Date -
Sep 18, 2014
app pub date -
Mar 13, 2013
filing date -
Mar 13, 2013
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Abstract
Provided herein are compositions and methods useful for preparing and analyzing a sample on a substrate by matrix assisted laser desorption ionization (MALDI) mass spectrometry (MS). In some embodiments, compositions provided herein comprise a substrate, matrix and nanoparticles, and sometimes comprise one or more additives and sometimes an analyte. Compositions provided herein sometimes comprise nanoparticles that include or are made up of silicon dioxide.
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