Gene targeting vector, and method for using same

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United States of America Patent

PATENT NO 9303272
APP PUB NO 20140335621A1
SERIAL NO

14364922

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Abstract

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Provided is a gene targeting vector that enables highly efficient gene targeting. The gene targeting vector has a structure comprising a positive selection marker flanked by a DNA homologous to a 5′-upstream region of a target site and a DNA homologous to a 3′-downstream region of the target site, wherein a splice acceptor site and a DNA sequence allowing for bicistronic expression are added 5′-upstream of the positive selection marker, and another splice acceptor site is also added 5′-upstream of the DNA homologous to the 5′-upstream region of the target site.

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Patent Owner(s)

Patent OwnerAddress
PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY22-2 SETO KANAZAWA-KU YOKOHAMA-SHI KANAGAWA 2360027

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adachi, Noritaka Yokohama, JP 11 81

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges4317336334866191291232201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +02505007501000125015001750200022502500275030003250350037504000425045004750

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11.5 Year Payment $7400.00 $3700.00 $1850.00 Oct 5, 2027