Betulonic and betulinic acid derivatives
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United States of America Patent
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Apr 5, 2016
Grant Date -
Mar 6, 2014
app pub date -
Nov 8, 2013
filing date -
Mar 7, 2006
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Abstract
The present invention relates to betulonic and betulinic acid derivatives and, in particular, to C-28 and C-3 derivatives. The present invention relates to betulonic acid esters, and dihydro-betulonic acid esters. Betulinic acid and derivatives thereof may be bound to a poly(alkylene glycol) (PAG) such as poly(ethylene glycol). Binding may be via a linker, such as a diamine, an amino acid, a peptide, an ester or a carbonate.
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