sGCalphal inhibiting compositions

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United States of America Patent

PATENT NO 9301991
SERIAL NO

14069790

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Abstract

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The present invention provides materials and methods useful to treat various sGCα1-expressing cancers. Materials include peptides which interfere with sGCα1's pro-survival functions, thereby resulting in apoptosis of sGCα1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF TOLEDO2801 W BANCROFT STREET TOLEDO OH 43606

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cai, Changmeng Newton, US 6 20
Chen, Shao-Yong Brookline, US 8 20
Hsieh, Chen-Lin Brighton, US 6 20
Shemshedini, Lirim Ypsilanti, US 6 20

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