Diagnostic methods for determining prognosis of non-small cell lung cancer
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United States of America Patent
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Mar 22, 2016
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May 5, 2011
app pub date -
Oct 25, 2010
filing date -
Oct 26, 2009
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Abstract
The present disclosure provides methods for identifying early stage non-small-cell lung cancer (NSCLC) patients who will have an unfavorable prognosis for the recurrence of lung cancer after surgical resection. The methods are based in part on the discovery of chromosomal copy number abnormalities that can be used for prognostic classification. The methods preferably use fluorescence in situ hybridization with fluorescently labeled nucleic acid probes to hybridize to patient samples to quantify the chromosomal copy number of these genetic loci.
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