Thieno-pyrimidines, useful as potassium channel inhibitors

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United States of America Patent

PATENT NO 9290511
APP PUB NO 20140371203A1
SERIAL NO

14358722

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Abstract

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The present invention provides compounds of formula (I): (Formula (I); wherein A, R1, R2, R3I, V, X, and Z are defined herein, which are potassium channel inhibitors. The invention further provides pharmaceutical compositions comprising the compounds of formula (I) and their use in therapy, in particular in treatment of diseases or conditions that are mediated by Kir3.1 and/or Kir3.4 or any heteromultimers thereof, or that require inhibition of Kir3.1 and/or Kir3.4 or any heteromultimers thereof.

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Patent Owner(s)

Patent OwnerAddress
XENTION LIMITEDICONIX PARK LONDON ROAD PAMPISFORD CAMBRIDGE CAMBRIDGESHIRE CB22 3EG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blunt, Richard Cambridge, GB 3 17
Brown, Lindsay Cambridge, GB 13 194
Chan, Fiona Cambridge, GB 2 17
Edwards, Simon D Cambridge, GB 11 110
Hartzoulakis, Basil Cambridge, GB 14 46
John, Derek Edward Cambridge, GB 11 50
Madge, David Cambridge, GB 9 42

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