Hypervalent radioactive astatine or iodine compounds, and preparation methods thereof
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United States of America Patent
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Mar 22, 2016
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app pub date -
Feb 2, 2011
filing date -
Feb 3, 2010
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Abstract
The present invention relates to a compound having formula (I): wherein: —X is in particular 125I Or 211At; —R1 and R′1 are independently from each other chosen preferably from the group consisting of electron-withdrawing groups and alkyl groups; —R2 is chosen from the group consisting of: H, alkyl groups, functional groups being able to bind a vector, and functional groups having targeting properties which make the compound of the invention a vector itself; —Z is a heteroatom, R5, R8 and R9 are preferably H; —Y is preferably an electron withdrawing group.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C07F:ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CO....
- C07D:HETEROCYCLIC COMPOUNDS
- C07C:ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07B:GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS TH....
- A61M:DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE B....
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