Apparatus for reducing variation in sample temperatures in a liquid chromatography system
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United States of America Patent
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Mar 22, 2016
Grant Date -
Jan 24, 2013
app pub date -
Jan 11, 2011
filing date -
Jan 11, 2010
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Abstract
Described is an apparatus for reducing a temperature variation of a liquid chromatography sample. A tray drive using at least one of linear or rotational motion moves a sample tray along a path inside a sample compartment of the liquid chromatography system. A control module coordinates the movement of the sample tray by the tray drive and the movement of a sample needle by a needle drive so that any sample in the sample tray can be injected into the mobile phase of the system during a sample load operation. The tray drive is also used to move the sample tray along the path during a temperature averaging period when no loading occurs. Differences in sample temperatures due to variations in the air temperature at different locations inside the sample compartment are reduced, leading to more accurate and repeatable chromatographic measurement results.
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