Functional brown adipose tissue imaging technique

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United States of America Patent

PATENT NO 9283317
APP PUB NO 20140275969A1
SERIAL NO

13841945

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Abstract

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Disclosed embodiments for assessing brown adipose tissue use imaging of metabolic contrast agents. For example, activated brown adipose tissue may be assessed by evaluating a difference in production of the hyperpolarized 13C metabolic contrast agent from a pre-polarized 13C metabolic contrast agent precursor before and after exposure of the subject to an activating event or agent. In one embodiment, the subject is given a dose of norepinephrine, and the production of the hyperpolarized 13C metabolic contrast agent before and after the dose is assessed.

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Patent Owner(s)

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SUNNYBROOK RESEARCH INSTITUTEONTARIO CANADA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Albert Po-Fu Toronto, CA 3 14
Cunningham, Charles H Toronto, CA 18 182
Lau, Angus Zoen Headington, GB 1 7

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