Functional brown adipose tissue imaging technique
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United States of America Patent
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Mar 15, 2016
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Sep 18, 2014
app pub date -
Mar 15, 2013
filing date -
Mar 15, 2013
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Abstract
Disclosed embodiments for assessing brown adipose tissue use imaging of metabolic contrast agents. For example, activated brown adipose tissue may be assessed by evaluating a difference in production of the hyperpolarized 13C metabolic contrast agent from a pre-polarized 13C metabolic contrast agent precursor before and after exposure of the subject to an activating event or agent. In one embodiment, the subject is given a dose of norepinephrine, and the production of the hyperpolarized 13C metabolic contrast agent before and after the dose is assessed.
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