Methods for increasing the stabilization of hypoxia inducible factor-α

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United States of America Patent

PATENT NO 9278930
APP PUB NO 20150157617A1
SERIAL NO

14628261

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Abstract

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Disclosed herein are methods for controlling the activity of hypoxia-inducible transcription factor 1-alpha (HIF-1α) and diseases, conditions, or syndromes related thereto, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia. Further disclosed are pharmaceutical compositions comprising HIF-1α prolyl hydroxylase inhibitors useful in treating diseases, conditions, and/or syndromes related thereto the activity of HIF-1α.

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Patent Owner(s)

Patent OwnerAddress
THE PROCTOR & GAMBLE COMPANY1 P&G PLAZA CINCINNATI OH 45202

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gardner, Joseph H Cincinnati, US 18 309
Shalwitz, Robert Bexley, US 65 1155

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