Process for making crystals
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United States of America Patent
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Mar 8, 2016
Grant Date -
Jul 29, 2010
app pub date -
Jun 17, 2008
filing date -
Jun 18, 2007
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Abstract
A process for preparing an emulsion or a dispersion comprising crystalline particles of at least one active principal that comprises contacting a solution of at least one solute in a solvent or mixture of solvents in a first flowing stream with a non-solvent in a second flowing stream wherein the non-solvent and solvent are not miscible with each other, so as to form an emulsion or a dispersion. Super saturation is brought about by suitable means, and the emulsion or dispersion is subjected to ultrasonic irradiation to mediate crystal nucleation.
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