toxin preparation from infant botulism pathogen

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United States of America Patent

PATENT NO 9278133
APP PUB NO 20100173841A1
SERIAL NO

12447351

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Abstract

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A novel type A botulinum toxin preparation is provided. A neuromuscular transmission blocking agent comprising as an active ingredient a highly purified type A botulinum toxin from Clostridium botulinum as infant botulism pathogen and a medicament for treating a disease with a muscle overactivity comprising as an active ingredient said toxin. In particular, the medicament of the present invention, as compared to the conventional known botulinum toxin preparations, has rapid efficacy of potential and is less diffusive and thus, having a broader safety margin, may be used as therapeutic medicament for decreasing local, muscle overactivity in a disease with a muscle overactivity.

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Patent Owner(s)

Patent OwnerAddress
KM BIOLOGICS CO LTD1-6-1 OKUBO KITA-KU KUMAMOTO-SHI KUMAMOTO 860-8568

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goto, Yoshitaka Kumamoto, JP 23 160
Harakawa, Tetsuhiro Kumamoto, JP 3 7
Kaji, Ryuji Naruto, JP 6 17
Kosaki, Shunji Tondabayashi, JP 1 2
Nakano, Hirotoshi Kumamoto, JP 2 7
Okuda, Sachio Kumamoto, JP 6 11
Shinmura, Miho Kumamoto, JP 3 6
Torii, Yasushi Kumamoto, JP 12 51

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