Chimeric avian-based screening system containing mammalian grafts
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United States of America Patent
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Mar 1, 2016
Grant Date -
Jul 4, 2013
app pub date -
Dec 3, 2012
filing date -
Jun 28, 2004
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Abstract
The present invention relates to animal model systems comprising a chimera between an avian embryo and a mammalian organism. Specifically, chimeric model systems comprising normal, diseased or genetically transformed mammalian cells and tissues transplanted into avian embryos, and uses thereof for in vivo testing of drugs and therapeutic modalities are disclosed.
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