Depletion of host cell components from live vector vaccines

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United States of America Patent

PATENT NO 9273289
APP PUB NO 20130273636A1
SERIAL NO

13988986

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Abstract

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It is desirable to produce live vaccines, which are highly attenuated and which do only contain minimal or no animal-derived components. The production of highly attenuated live viruses can be better achieved when using specifically designed cell lines as producer substrate as opposed to using less defined primary cells. However, live viruses, thus produced comprise undesirable components from the cell lines and cell culture. The present invention relates to methods of production and purification of live enveloped viruses, which are suitable for vaccination.

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Patent Owner(s)

Patent OwnerAddress
PROBIOGEN AG13086 BERLIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bernhardt, Holger Berlin, DE 2 0
Hartmann, Stefan Berlin, DE 16 108
Jordan, Ingo Berlin, DE 14 43

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