Antibody for detecting DNA damage in cells utilizing cell membrane surface antigen Ly6D
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United States of America Patent
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Mar 1, 2016
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Jan 2, 2014
app pub date -
May 10, 2013
filing date -
May 10, 2012
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Abstract
To provide a method for detecting cellular DNA damage by specifically recognizing molecules responsive to DNA strand breaks. A method for detecting DNA damage in cells, which comprises administering in vivo, to cells, an antibody against a cell membrane surface antigen that is expressed in cells undergoing DNA strand breaks to a greater extent than in cells not undergoing DNA strand breaks in an environment that causes DNA damage, and analyzing the expression status of the cell membrane surface antigen.
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