α4β7 peptide dimer antagonists

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United States of America Patent

PATENT NO 9273093
APP PUB NO 20140193465A1
SERIAL NO

14050349

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Abstract

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The invention relates to disulfide-rich dimer molecules which inhibit binding of α4β7 to the mucosal addressin cell adhesion molecule (MAdCAM) in vivo, and show high selectivity against α4β1 binding.

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Patent Owner(s)

Patent OwnerAddress
PROTAGONIST THERAPEUTICS INC7707 GATEWAY BOULEVARD NEWARK CA 94560-1160

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhandari, Ashok Pleasanton, US 67 947
Mattheakis, Larry C Cupertino, US 39 878
Patel, Dinesh V Fremont, US 71 1372

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