Agents for the molecular imaging of serine-protease in human pathologies

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United States of America Patent

PATENT NO 9272054
APP PUB NO 20130243691A1
SERIAL NO

13990845

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Abstract

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The present invention is directed to the use of an irreversible ligand of a serine protease selected from the group consisting of leukocyte elastase, thrombin, tissue plasminogen activator (t-PA) and plasmin for the molecular imaging of said serine protease and the diagnosis of pathophysiological conditions associated with said serine protease activity.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)101 RUE DE TOLBIAC PARIS 75013
PHARMALEADSPARIS FRA
UNIVERSITE PARIS DIDEROT - PARIS 775013 PARIS
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS3 AVENUE VICTORIA PARIS F-75004

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fournie-Zaluski, Marie-Claude Paris, FR 26 108
Leguludec, Dominique Paris, FR 2 0
Michel, Jean-Baptiste Paris, FR 21 154
Poras, Hervé Paris, FR 11 10
Rogues, Bernard Paris, FR 1 0
Rouzet, François Paris, FR 1 0

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