Apolipoprotein AIV as an antidiabetic peptide
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United States of America Patent
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Feb 23, 2016
Grant Date -
Sep 10, 2015
app pub date -
May 5, 2015
filing date -
Jan 19, 2011
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Abstract
Methods for treating type two diabetes mellitus in a subject in need thereof and pharmaceutical compositions for the treatment of type two diabetes mellitus are disclosed. The methods include administering an effective amount of apolipoprotein A-IV to the subject. The pharmaceutical composition includes apolipoprotein A-IV formulated for administration to a subject for the treatment of type two diabetes mellitus. Also disclosed are methods for substantially restoring glucose tolerance in a subject in need thereof to a normal level and methods for lowering blood glucose levels in a subject in need thereof.
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