Treatment of metabolic-related disorders using hypothalamic gene transfer of BDNF and compositions therefor
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United States of America Patent
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Feb 23, 2016
Grant Date -
Nov 24, 2011
app pub date -
Mar 27, 2009
filing date -
Mar 27, 2008
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Abstract
Described herein is a system which uses a gene therapy particle that includes at least one gene, cDNA, fragment or analogue of at least one neurotropin that binds to the trkB receptor or the trkB receptor itself. The gene therapy particle is capable of being delivered to a subject in need thereof for therapy of a metabolic disorder. In a particular aspect, this invention is directed to an inventive method that demonstrates a remarkable efficacy on lowering body weight.
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