Transdermal patch containing Rotigotine

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United States of America Patent

PATENT NO 9265752
APP PUB NO 20110027345A1
SERIAL NO

12667915

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Abstract

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A Rotigotine-containing composition having a matrix mixture system formed from a polyvinylpyrrolidone and a combination of an acrylic pressure-sensitive adhesive with a silicone pressure-sensitive adhesive. The polyvinylpyrrolidone may be present in an amount of about 1-10% by weight in matrix mixture system. The acrylic pressure-sensitive adhesive may be present in an amount of about 1-25% by weight in the matrix mixture system. The silicone pressure-sensitive adhesive may be present in an amount of about 65-98% by weight in the matrix mixture system. The composition further includes 1-40% of Rotigotine on the basis of the total weight of the composition. The composition provides improved properties in the solubility, release and initial penetration level of Rotigotine. Also disclosed is a transdermal patch that includes the Rotigotine-containing composition, as well as methods of manufacturing and using the Rotigotine-containing composition.

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Patent Owner(s)

Patent OwnerAddress
JIANGSU KANGBEIDE PHARMACEUTICALS CO LTDZHONGSHAN TECHNOLOGY PARK NANJING JIANGSU 211500

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chi, Guohua Beijing, CN 2 16
Du, Hongguang Beijing, CN 4 16
Lian, Hongjun Beijing, CN 2 16
Liu, Xiquan Beijing, CN 4 16
Lu, Yucheng Beijing, CN 20 92
Shi, Xiaoyan Beijing, CN 100 421
Song, Li Beijing, CN 71 895
Wang, Li Beijing, CN 972 6677
Wang, Shuming Beijing, CN 13 66
Xue, Huiyong Beijing, CN 2 40
Zhang, Enhong Beijing, CN 3 40
Zhong, Xuying Beijing, CN 3 40

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